Neuroimmunology of Multiple sclerosis

Yale School of Medicine, New Haven, United States

David Hafler | moderator
Overview of the Cause of Multiple sclerosis

David Pitt
Astrocyte and the Neuropathology of Multiple sclerosis

Tomokazu Sumida
Loss of Immune regulation in Multiple sclerosis

Erin Longbrake
New Clinical Trials in Multiple sclerosis

How Open Science is Changing Personalized Medicine in Neurodegenerative Diseases and Disorders

Montreal Neurological Institute-Hospital, McGill University, Canada

Stefano Stifani | moderator
Welcome and introduction

Jason Karamchandani
The C-BIG Platform: A Novel Open Science Combined Patient Registry and Multi-Modal Repository

Tom Durcan
The Neuro’s Early Drug Discovery Unit: Opening up discovery through collaboration and outreach

Jo-Anne Stratton
Open Science in the works: a deeper understanding of Parkinson’s Disease immunology

Sali Farhan
Leveraging Open Science to advance gene discovery in neurodegenerative diseases

Annabel Seyller
Closing remarks

Demyelination & remyelination in neurodegeneration: From molecule to clinical application

Karolinska Institutet, Stockholm, Sweden

Ole Petter Ottersen
Opening speech

Maja Jagodic
Molecular markers of Multiple Sclerosis development and progression

Tobias Granberg
In vivo imaging and quantification of demyelination and remyelination

Fredrik Piehl, Gonçalo Castelo-Branco, Chiara Starvaggi Cucuzza
Moderators

PET molecular imaging in “brain neurodegenerative diseases"

UniSR – Università Vita-Salute San Raffaele, Milan, Italy

Daniela Perani | moderator
Introducing and chairing

Rik Ossenkoppele
Assessment of Alzheimer’s disease pathology in the living human brain

Gael Chetelat
Evaluating the brain reserve effect on neurodegeneration

Valentina Garibotto
How artificial intelligence can support our investigation of the brain

Multiple Sclerosis: The Gut-Brain Connection

Max Planck Institute of Neurobiology, Munich, Germany

Hartmut Wekerle | moderator
Introduction: The gut-brain axis in MS

Naoto Kawakami
Autoimmune T cell traffic gut to brain

Amira Metwaly
Microbiota and human disease

Lisa Gerdes
MS twin study

Anneli Peters
Microbiota and MS – From model to human MS

Innate immunity in neurodegenerative diseases

Harvard Medical School, Brigham and Women’s Hospital, Ann Romney Center for Neurological Diseases, Boston, United States

Francisco Quintana
Astrocytes

Oleg Butovsky
Microglia

Rafael Machado Rezende
Nasal anti-CD3 treatment of neurodegenerative diseases

Howard Weiner
Protollin treatment of Alzheimer’s disease

Parkinson’s disease from pathophysiology to treatment

Juntendo University Hospital, Neurology Department, Tokyo, Japan

Nobutaka Hattori
Two hundred years’ history of Parkinson’s disease

Taku Hatano
The accumulation and propagation of alpha synuclein in synucleinopathies

Shinji Saiki
Novel biomarkers for detection of early Parkinson’s disease and its progression

Taiji Tsunemi | moderators
Small extracellular vescicles matter in the development of Parkinson’s disease

Monitoring Neurodegeneration in Multiple Sclerosis

UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco, United States

Steve Hauser | moderator
Welcome and Introduction

Riley Bove
Visualizing Neurodegeneration in Real-time: A BRIDGE to the Clinic

Valerie Block
Stepping into the Future – Remote Monitoring as a Signal for MS Progression

Roland Henry
Spinal Cord Atrophy Precedes and Predicts Progressive MS and Silent Disability Worsening

Michael Wilson
Antibody Targets in Multiple Sclerosis

Sergio Baranzini
Linking Microbes and Diet to Neurodegeneration and Clinical Outcomes: Massive Data Integration with a Knowledge Graph

Stephen Hauser
Speaker Roundtable Discussion

Neuroimaging in dementia

Tianjin Medical University General Hospital, Neurology Department, Tianjin, China

Nan Zhang | moderator
Opening

Qin Chen
Neuroimaging in familial frontotemporal lobar degeneration

Jun Wang
Beijing Aging Brain Rejuvenation Initiative (BABRI): Revealing Neuroimaging Indicators

Mengya Xing
Cerebral blood flow pattern measured with Arterial Spin Labeling in subcortical ischemic vascular dementia

Nan Zhang
Discussion

Inflammation and immunological responses in neurodegenerative diseases

German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Bonn, Germany

Sleep in neurodegenerative diseases

Hôpital de la Pitié-Salpêtrière, Sorbonne University AP-HP, Neurology Department and Paris Brain Institute, Paris, France